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Active substance-Fentanyl (Phentanylum). Fentanyl and its derivatives and alpha methylfentanyl, three methylfentanyl (slang for "the white Chinese"), meperidine, parafluorofentanyl are the most terrible and deadly drug existing in the world. On chemical structure partially similar to promedolum. It has a strong, but short-term (for the occasional introduction) analgesic effect.

Fentanyl is used in anesthesia as one of the strongest drugs, neurosurgeons which is used in critical heavy operations on the brain, especially when you need to carry out the operation without loss of consciousness. The use of this drug must necessarily be accompanied by a doctor of the highest qualification, availability of special equipment and special conditions of the intensive care unit.

Therapeutic

Opioid narcotic analgesics
Testimony
Premedication before surgery, induction of anesthesia, postoperative analgesia, neuroleptic analgesia, pain syndrome, chronic pain in cancer patients. Local skin reactions - rash, erythema, pruritus (disappear within 24 hours after patch removal).
Contraindications
Hypersensitivity, bronchial asthma, depression of the respiratory center, cranial hypertension, obstetric surgery, drugs, pregnancy, breastfeeding.

Dosage

Fentanyl Side Effects:

- hypoventilation;
- respiratory depression up to the stop (in high doses);
- bronchospasm;
- paradoxical CNS stimulation;
- confusion;
- hallucinations;
- short-term muscle rigidity (including infants);
- bradycardia;
- nausea;
- vomiting;
- constipation;
- hepatic colic;
- urinary retention;
- amblyopia; - patch: local skin reactions - rash, erythema, pruritus (disappear within 24 hours after patch removal).

Precautionary measures

Abolition of the drug is produced gradually. When used in large doses and adynamic malnourished patients may develop secondary respiratory depression associated with the release of fentanyl in 1-2 hours after the injection into the gastric lumen and the subsequent resorption. Application of the plaster is not recommended in case of acute or postoperative pain (due to the impossibility of matching the dose over a short period of treatment and risk of hypoventilation), for women of childbearing age, and requires caution chronic, including obstructive pulmonary disease (possibly depression of the respiratory center), impairment of consciousness, coma, brain tumors, bradyarrhythmias, hepatic and renal failure, in the elderly and children. When using the patch to avoid direct exposure to external heat sources (heaters, saunas, sunbathing, etc.) is advised. During treatment patient should not engage in potentially hazardous activities that require increased attention and psychomotor reactions.

Overdose

Due to the fact that fentanyl has very high toxicity, even if a minor overdose of fentanyl may cause oppression cough center, cramps (severe constriction of the pupils), hallucinations, reduced secretory activity of the stomach, irritable bowel chemoreceptors, decreasing urine output, reducing the basal metabolic rate, lowering the temperature of body, dizziness, headaches, increased tone of smooth muscle, bronchial spasm, spasm in the ureters, pain when urinating, the suppression of the longitudinal intestinal motility, increased cross-intestinal motility, increased tone of the gastric antrum, inhibition of basal secretion, slowing the passage of intestinal contents, dyskinesia of the colon , blurred vision, dyspepsia, damage to the gastric mucosa, interstitial tissue damage, pulmonary edema, hypoxia, bradycardia, heart failure, a significant inhibition of the respiratory center, stupor, respiratory center of the brain and respiratory arrest.

With long-term use of fentanyl in doses even slightly higher than therapeutic, may develop diseases such as gastritis, gastric ulcer and duodenal ulcer. Also the use of fentanyl can cause liver damage vascular endothelium, hepatocyte damage and cirrhosis of the liver, liver toxicity due to fentanyl.

Fentanyl: Composition

Fentanyl Injection is available in the form of a 0.005% solution in ampoules of 2.0 and 5.0 ml.

Fentanyl is also included in a TTS having a special kind of adhesive membrane regulating the release rate of the active substance.

Synonyms:

Fentanyl citrate, Sentonil, Fentanest, Sublimaz, Galdid, Leptanal.

Additionally:

Fentanyl is also part of a combined drug Talamonal.

Terms of medicine safekeeping

Fentanyl belongs to the list A and must be kept by the rules established for the keeping of narcotic drugs. Preparation can be stored at a temperature not higher than 25 ° C centigrade. The storage place should be protected from moisture and direct sunlight. Keep away from children.

How and where to buy Fentanyl?

Many patients and dependents try to find out where to buy this drug. Fentanyl is released by a special recipe in certain pharmacies and it is practically no easy to get it by another means. That is why it would be suitable to ask “by means of whom to order or buy Fentanyl. If having the recipe you may buy fentanyl online in your local pharmacy.

How Can I Get Fentanyl Without a Prescription?

The value is varied from 50$ to 250$ depending on species. Repiting the drug and its dose may be appointed only with the special permission of doctor. In case If the local pharmacy does not have this medicine and you do not know where to buy Fentanyl you may also use global network which can prompt you how to buy Fentanyl.There are a lot of specially medically oriented sites which will asist you how to buy Fentanyl. Inspite of that it is no easy to buy Fentanyl online too, that is why most do not try to order Fentanyl legally. There are lost of black markets all over the world that does not obstruct dependents to order Fentanyl. To buy Fentanyl online having a medical permission or to buy Fentanyl illegally without knowing the quality is your choice.

Usage no in medical measures

It is much stronger than heroin. Dangerous drugs that doctors sometimes use as an anesthetic or analgesic.

How does it look?

The fine crystalline white powder.

How to use?

Intravenously, smoked or snorted. When injected intravenously, and acts immediately within 4-6 hours.

Why use?

Eat covers euphoria, a feeling of warmth and drowsiness, he feels safe distance from all sorts of adversity.

Why harmful?

Fentanyl quickly cause severe mental and physical dependence. Dependent on the fentanyl can not renounce the use of the drug and needs it several times a day to feel normal. To get rid of this dependence is extremely difficult.

To obtain the same effect, it is necessary increasing amount of fentanyl.

If you constantly inject for several hours and does not receive the next dose, then it appears the strongest signs of alienation: joint pain, drooling, and tears, insomnia, cramps and chills.

Lost interest in previous activities and friends, all of life is focused only on how to get the next dose. Long-term use causes impotence.

The constant use of fentanyl requires a lot of money, so many addicts become criminals.

If you share with someone else when injected fentanyl syringe, there is a high probability of contracting HIV. When using a common syringe to apply and other infectious diseases, such as hepatitis.

Inept injection may cause serious harm or even kill.

How to recognize the dependents?

- constricted pupils;
- slow breathing;
- calm, in a good mood;
- ightweight speech disorders tired;
- no appetite;
- sleepy;
- needle marks on his arm or body.

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